Holistic Hercules Nattokinase 10,000 FU

Nattokinase 10,000 FU: Full-Dose Circulation Support

Japan eats natto almost every day. Most Americans have never tried it. Inside it is nattokinase, the enzyme that helps your body break down fibrin, the sticky protein that makes blood thicker and slower as you age. We put the full 10,000 FU in 3 capsules, without the smell or the slime.*

  • 🩸Helps break down fibrin for smoother blood flow*
  • ❤️Supports healthy circulation & everyday heart health*
  • 🔬10,000 FU, the dose range where research saw results
  • 💊3 capsules a day · 80 days in every bottle
30 Day Money Back Guarantee Included
$39.99 Add to cart
✓ Free shipping✓ Ships in 1–3 business days✓ 30-day guarantee
Description
Holistic Hercules Nattokinase delivers 10,000 FU of nattokinase in every 3-capsule serving: the enzyme from natto, the fermented soybean dish Japan has eaten for over 1,000 years. It's paired with CoQ10, turmeric, aged garlic, grape seed and dandelion root (500 mg blend), plus bromelain (10 mg) and pine bark (5 mg). 240 vegetarian capsules per bottle, an 80-day supply. Gluten, dairy and tree nut free.
The Results
Most people feel nothing in the first week. The changes people describe, like warmer hands and feet and lighter legs at night, usually show up after a few weeks of taking it every day. Enzymes work with your body, not overnight, so take 3 capsules daily with a meal and give it time. Results vary.*
30 Day Guarantee
Take it every day. If you're not happy within 30 days, email support@holistichercules.com and we'll refund you in full. No questions asked.
Shipping & Returns
Orders ship within 1–3 business days and usually arrive in 2–3 business days. Not satisfied? Our 30-day money-back guarantee has you covered. Contact support@holistichercules.com to start a return.

Frequently Asked Questions

Common questions we hear from customers

How do I take it?
3 capsules a day with a glass of water, preferably with a meal. One bottle has 240 capsules, so it lasts 80 days.
I'm on a blood thinner or daily aspirin. Can I take this?
Talk to your doctor first. Nattokinase supports breaking down fibrin, so it can add to the effect of blood thinners and aspirin. The same goes if you have a bleeding disorder. Stop it 2 weeks before any surgery or dental procedure.
Can I take it with my other medications?
Tell your doctor what you're taking before you start, and never stop a prescription on your own. Nattokinase is a supplement, not a replacement for anything your doctor prescribed.
Aren't all nattokinase supplements the same?
No. FU measures how active the enzyme is. In a 12-month clinical study of 1,062 adults, 3,600 FU a day was found ineffective and 10,800 FU a day was effective on the outcomes measured. Most brands sell 2,000 to 4,000 FU. Ours is 10,000 FU per serving.
When will I notice anything?
Most people feel nothing in week one. Changes people describe usually show up after a few weeks of daily use. Results vary, and you're covered by the 30-day guarantee either way.
Why not just eat natto like they do in Japan?
You can! You'd need four or five packs a day to reach 10,000 FU, and the smell and sticky texture are a lot for most people. The capsules give you the same enzyme without the breakfast.
A multi-generation Japanese family sharing a meal

The part nobody talks about

Why Sluggish Circulation Isn't a Willpower Problem

Everyone talks about diet and cholesterol. Almost nobody talks about fibrin, the sticky protein that builds up as you age and makes blood thicker and slower to move. You can eat clean and walk every day, and still feel like you're running on thick, slow fuel.

  • Cold hands and feet, even when the room is warm
  • Legs that feel heavy on the stairs
  • Pins and needles when you lie down at night
  • That "am I next?" feeling whenever family health comes up
A bowl of natto, fermented soybeans, lifted with chopsticks

Why Japan?

Japan Eats This Every Day. Most Americans Never Have.

Natto, sticky fermented soybeans, has been a Japanese breakfast staple for over 1,000 years. Japan also has one of the longest life expectancies in the world. It's not one thing, but natto is the reason researchers started paying attention to the enzyme inside it.

That enzyme is nattokinase, first identified in 1980 by Japanese researcher Dr. Hiroyuki Sumi. The catch: to get 10,000 FU from food, you'd have to eat four or five packs of natto a day.

1,000+years on the Japanese table
4–5packs of natto for 10,000 FU
3capsules. No smell, no slime.

The Japanese Enzyme

Break Down the Fibrin, Not Just the Symptom

Holistic Hercules Nattokinase is fibrinolytic: it helps your body break down fibrin, at the 10,000 FU dose range research actually used.*

Helps Break Down Fibrin*
Heart & Circulation*
Healthy Blood Flow*
Warmer Hands & Feet*

Illustration only. Results vary.

How it creeps up

How Sluggish Circulation Shows Up Over Time

Illustration of a few fibrin strands in a blood vessel
STAGE 1

The Quiet Years

Nothing hurts. Nothing warns you. Fibrin slowly builds up in your blood through all the years you felt completely fine.

Illustration of more fibrin strands slowing blood cells
STAGE 2

You Start Noticing

Cold feet. Heavy legs. A pause halfway up the stairs you never used to need. Your blood is moving slower than it used to.

Illustration of a dense fibrin mesh in a blood vessel
STAGE 3

You Start Wondering

You eat better, walk more, and still feel like you're running on thick, slow fuel. That's when most people go looking for answers.

Why 10,000 FU matters

The Dose Is Everything

FU (fibrinolytic units) measures how active the enzyme is. In the largest human study, the lower dose didn't work on the outcomes measured. The higher dose did.

05,00010,000 2,000–4,000Most brands 3,600Study: ineffective 10,800Study: effective 10,000Holistic Hercules
Too low in the studyEffective dose in the studyOur dose per serving

Source: Chen H. et al., "Effective management of atherosclerosis progress and hyperlipidemia with nattokinase: A clinical study with 1,062 participants," Frontiers in Cardiovascular Medicine, 2022. doi.org/10.3389/fcvm.2022.964977. 12-month study; a correction was published Dec 2022, and several authors are affiliated with a nattokinase manufacturer. Holistic Hercules Nattokinase was not tested in this study and is not intended to diagnose, treat, cure or prevent any disease.

What to expect

What to Expect as Support Builds Over Time

Week 1–2: Easy Start

3 capsules with a meal. The enzyme gets to work. You probably won't feel anything yet, and that's normal.

  • 3 capsules a day, with food
  • No loading phase, no timing rules
Week 3–5: First Signs

The first changes people describe have nothing to do with a lab report.*

  • Warmer hands and feet*
  • Lighter legs at night*
Week 6–12: Momentum

Stay consistent and the routine starts to feel like part of your day.*

  • Stairs and evening walks can feel easier*
  • More energy for the things you like doing*
Day 80: Bottle Done

One bottle covers the whole stretch. The study that found results ran a full 12 months, so this is a long game.

  • Keep going if you like how you feel
  • Buy 2 + Get 1 Free covers 240 days
Natto, the Japanese food nattokinase comes from

By the numbers

Everything in One Bottle

What you get in every bottle of Holistic Hercules Nattokinase.

10,000 FU
Full daily dose
The dose range where research saw results, in 3 capsules
80 days
In every bottle
240 vegetarian capsules, about $0.24 a day
8
Ingredients
Nattokinase, CoQ10, turmeric, aged garlic, grape seed, dandelion root, bromelain and pine bark

30-DayMoney-Back Guarantee

Don't take our word for it. Take it for 30 days.

  • Take 3 capsules every day
  • Not happy? Email us within 30 days
  • Full refund, no questions asked
Try it risk-free
Holistic Hercules Nattokinase, 240 capsules, 80-day supply

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Results vary.

Consult your doctor before use if you are pregnant or nursing, take blood thinners or antiplatelet medication, have a bleeding disorder, or have surgery scheduled.

Get 10,000 FU · $19.99